POLR3B

Across TCGA patient cohorts, POLR3B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,468 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR3B-associated proteins across cancer lineages are SRSF9, SART3, and SCYL2. Each is linked with POLR3B in more than 6 cancer types. Because this analysis shows association rather than direction, both POLR3B-to-partner and partner-to-POLR3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3B versus SRSF9 in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3B→partner) and Y-score (partner→POLR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.420	+0.474	<.001	<.001	3	7
OV	SART3 →	+0.439	+0.612	<.001	<.001	3	6
LSCC	SCYL2 →	+0.264	+0.581	<.001	<.001	3	6
GBM	SNRPD2 →	+0.241	+0.301	<.001	<.001	3	6
LSCC	MBD3 →	+0.501	+0.439	<.001	<.001	3	6
OV	PRPF31 →	+0.298	+0.520	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,468 associations by consensus.

POLR3B vs SRSF9 — LSCC

Explore this scatter interactively →