POLR3B

Across TCGA cell cohorts, POLR3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POLR3B-associated GO terms across cancer lineages are snRNA transcription by RNA polymerase III, Transcription elongation-coupled chromatin remodeling, and rRNA 5'-end processing. Each is linked with POLR3B in more than 17 cancer types. Because this analysis shows association rather than direction, both POLR3B-to-partner and partner-to-POLR3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA transcription by RNA polymerase III grouped by POLR3B-low versus POLR3B-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3B→partner) and Y-score (partner→POLR3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	snRNA transcription by RNA polymerase III →	+0.082	+0.940	<.001	<.001	3	18
BONE	Transcription elongation-coupled chromatin remodeling →	+0.135	+0.730	<.001	<.001	3	17
LIVER	rRNA 5'-end processing →	+0.135	+0.638	<.001	<.001	3	16
LIVER	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.135	+0.638	<.001	<.001	3	16
SOFT_TISSUE	DNA-templated transcription termination →	+0.122	+0.928	<.001	<.001	3	16
BONE	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.128	+0.606	.008	.003	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

snRNA transcription by RNA polymerase III by POLR3B expression — BLOOD_Lymphoma

Explore this box plot interactively →