POLR2KP1

Across TCGA patient cohorts, POLR2KP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,189 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR2KP1-associated proteins across cancer lineages are DHX9, YTHDC1, and SSB. Each is linked with POLR2KP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both POLR2KP1-to-partner and partner-to-POLR2KP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR2KP1 versus DHX9 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2KP1→partner) and Y-score (partner→POLR2KP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.279	+0.902	<.001	<.001	3	6
GBM	YTHDC1 →	+0.313	+0.635	<.001	<.001	3	5
LUAD	SSB →	+0.269	+0.768	<.001	<.001	3	5
LSCC	ADNP →	+0.426	+0.790	<.001	<.001	3	5
GBM	IWS1 →	+0.272	+0.669	.001	<.001	3	5
GBM	RBBP5 →	+0.229	+0.482	.002	.008	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,189 associations by consensus.

POLR2KP1 vs DHX9 — LSCC

Explore this scatter interactively →