Across TCGA patient cohorts, POLR2J2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,224 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible POLR2J2-associated proteins across cancer lineages are MEPCE, DHX9, and POLR2E. Each is linked with POLR2J2 in more than 4 cancer types. Because this analysis shows association rather than direction, both POLR2J2-to-partner and partner-to-POLR2J2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J2→partner) and Y-score (partner→POLR2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MEPCE →	+0.358	+0.865	<.001	<.001	3	5
PDAC	DHX9 →	+0.199	+0.599	<.001	<.001	3	5
HNSC	POLR2E →	+0.237	+1.004	<.001	<.001	3	4
GBM	PRPF4 →	+0.243	+0.460	.007	.004	3	4
GBM	ARID4B_S295 →	+0.450	+0.463	<.001	.001	3	4
UCEC	PDLIM1 →	-0.379	-0.613	.005	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,224 associations by consensus.

Exploration

POLR2J2 survival (RNA) · tumor vs normal (RNA) · all POLR2J2 data types