Across TCGA pan-cancer cohorts, POLR2J2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of POLR2J2’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where POLR2J2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POLR2J2 is over-expressed in tumor.

ESCA and LIHC are the cancer types where POLR2J2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POLR2J2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	Male	All	+0.083	.049	1	view →
LIHC	Male	All	+0.010	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: POLR2J2 RNA expression & survival · all POLR2J2 data types