Across TCGA patient cohorts, POLR2J2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,667 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible POLR2J2-associated GO terms across cancer lineages are Negative regulation of DNA-templated transcription, elongation, Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage, and Obsolete histone H3-K4 methylation. Each is linked with POLR2J2 in more than 12 cancer types. Because this analysis shows association rather than direction, both POLR2J2-to-partner and partner-to-POLR2J2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2J2→partner) and Y-score (partner→POLR2J2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Negative regulation of DNA-templated transcription, elongation →	+0.111	+1.182	<.001	<.001	3	13
KIRC	Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.037	+0.025	<.001	<.001	3	10
READ	Obsolete histone H3-K4 methylation →	+0.043	+0.036	<.001	<.001	3	10
KIRC	Mitochondrial gene expression →	+0.025	+0.027	<.001	<.001	3	10
KIRC	Positive regulation of DNA metabolic process →	+0.019	+0.022	<.001	<.001	3	10
KIRC	Protein methylation →	+0.028	+0.028	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,667 associations by consensus.

Exploration

POLR2J2 survival (RNA) · tumor vs normal (RNA) · all POLR2J2 data types