POLR2H

Across TCGA cell cohorts, POLR2H RNA expression is significantly associated with the go_rna of many other GO terms, with 3,129 significant associations in total. BONE shows the largest number of these associations.

The most reproducible POLR2H-associated GO terms across cancer lineages are Maintenance of centrosome location, U4 snRNA 3'-end processing, and tRNA metabolic process. Each is linked with POLR2H in more than 13 cancer types. Because this analysis shows association rather than direction, both POLR2H-to-partner and partner-to-POLR2H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of centrosome location grouped by POLR2H-low versus POLR2H-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2H→partner) and Y-score (partner→POLR2H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Maintenance of centrosome location →	+0.146	+0.857	.001	.002	3	14
BONE	U4 snRNA 3'-end processing →	+0.189	+0.775	.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	tRNA metabolic process →	+0.060	+0.859	.002	<.001	3	10
BONE	Mitochondrial gene expression →	+0.107	+0.712	.001	<.001	3	10
LIVER	Substrate adhesion-dependent cell spreading →	-0.212	-0.765	.007	.004	3	10
URINARY_TRACT	Quinone metabolic process →	+0.088	+0.616	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,129 associations by consensus.

Maintenance of centrosome location by POLR2H expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →