POLR2G

Across TCGA cell cohorts, POLR2G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,148 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible POLR2G-associated GO terms across cancer lineages are Mitochondrial electron transport, succinate to ubiquinone, Regulation of attachment of mitotic spindle microtubules to kinetochore, and Positive regulation of attachment of mitotic spindle microtubules to kinetochore. Each is linked with POLR2G in more than 14 cancer types. Because this analysis shows association rather than direction, both POLR2G-to-partner and partner-to-POLR2G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, succinate to ubiquinone grouped by POLR2G-low versus POLR2G-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR2G→partner) and Y-score (partner→POLR2G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial electron transport, succinate to ubiquinone →	+0.076	+0.351	<.001	.001	3	15
STOMACH	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.132	+0.499	<.001	.001	2	14
BONE	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.176	+0.743	.008	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Deadenylation-dependent decapping of nuclear-transcribed mRNA →	+0.084	+0.555	<.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of attachment of spindle microtubules to kinetochore →	+0.122	+0.722	.002	.002	2	11
UPPER_AERODIGESTIVE_TRACT	Spliceosomal snRNP assembly →	+0.058	+0.519	.003	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,148 associations by consensus.

Mitochondrial electron transport, succinate to ubiquinone by POLR2G expression — LUNG_SCLC

Explore this box plot interactively →