POLR1G

Across TCGA patient cohorts, POLR1G RNA expression is significantly associated with the protein abundance of many other proteins, with 11,558 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR1G-associated proteins across cancer lineages are POLR1E, PUS7, and NOC4L. Each is linked with POLR1G in more than 8 cancer types. Because this analysis shows association rather than direction, both POLR1G-to-partner and partner-to-POLR1G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR1G versus POLR1E in LSCC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1G→partner) and Y-score (partner→POLR1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	POLR1E →	+0.380	+0.429	<.001	<.001	3	9
LUAD	PUS7 →	+0.386	+0.412	<.001	.002	3	7
BRCA	NOC4L →	+0.492	+0.563	<.001	<.001	3	6
BRCA	NOL10 →	+0.568	+0.612	<.001	<.001	3	6
OV	PES1 →	+0.489	+0.739	<.001	<.001	3	6
LSCC	WDR36 →	+0.380	+0.435	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,558 associations by consensus.

POLR1G vs POLR1E — LSCC

Explore this scatter interactively →