POLR1G

Across TCGA patient cohorts, POLR1G protein abundance is significantly associated with the RNA expression of many other genes, with 13,711 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible POLR1G-associated genes across cancer lineages are MYC, DCAF13, and C19orf48. Each is linked with POLR1G in more than 6 cancer types. Because this analysis shows association rather than direction, both POLR1G-to-partner and partner-to-POLR1G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR1G versus MYC in UCEC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1G→partner) and Y-score (partner→POLR1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYC →	+1.106	+0.257	<.001	<.001	3	7
UCEC	DCAF13 →	+0.594	+0.203	<.001	<.001	3	7
UCEC	C19orf48 →	+1.412	+0.206	<.001	<.001	3	7
UCEC	RPS21 →	+1.069	+0.211	<.001	<.001	3	7
BRCA	FBL →	+1.124	+0.546	<.001	<.001	3	6
UCEC	RPS19 →	+1.183	+0.160	.001	.003	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,711 associations by consensus.

POLR1G vs MYC — UCEC

Explore this scatter interactively →