POLR1G

Across TCGA patient cohorts, POLR1G mutation is significantly associated with the RNA expression of many other genes, with 1,909 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR1G-associated genes across cancer lineages are LINC01072, VWC2L-IT1, and MTCO1P52. Each is linked with POLR1G in more than 1 cancer types. Because this analysis shows association rather than direction, both POLR1G-to-partner and partner-to-POLR1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by POLR1G-low versus POLR1G-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1G→partner) and Y-score (partner→POLR1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC01072 →	+0.148	+5.345	<.001	.001	3	2
CESC	VWC2L-IT1 →	+0.085	+5.569	<.001	.002	3	2
CESC	MTCO1P52 →	+0.088	+5.837	<.001	.001	3	2
CESC	RPL30P16 →	+0.077	+4.539	<.001	.008	3	2
BLCA	RNU1-65P →	+0.262	+4.704	<.001	.005	3	2
UCEC	BIVM-ERCC5 →	+0.008	+1.941	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,909 associations by consensus.

LINC01072 by POLR1G expression — CESC

Explore this box plot interactively →