POLR1G

Across TCGA cell cohorts, POLR1G RNA expression is significantly associated with the go_rna of many other GO terms, with 4,017 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POLR1G-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, rRNA transcription, and Nucleolar large rRNA transcription by RNA polymerase I. Each is linked with POLR1G in more than 19 cancer types. Because this analysis shows association rather than direction, both POLR1G-to-partner and partner-to-POLR1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase I promoter grouped by POLR1G-low versus POLR1G-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1G→partner) and Y-score (partner→POLR1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transcription initiation at RNA polymerase I promoter →	+0.150	+1.651	<.001	<.001	3	20
LUNG_NSCLC_LUSC	rRNA transcription →	+0.149	+1.927	<.001	<.001	3	19
URINARY_TRACT	Nucleolar large rRNA transcription by RNA polymerase I →	+0.142	+1.265	<.001	<.001	3	19
OESOPHAGUS	Transcription by RNA polymerase I →	+0.135	+1.103	<.001	<.001	3	19
BLOOD_Myeloma	Ribosomal small subunit biogenesis →	+0.110	+1.295	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication →	+0.144	+1.228	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,017 associations by consensus.

Transcription initiation at RNA polymerase I promoter by POLR1G expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →