POLR1F

Across TCGA patient cohorts, POLR1F protein abundance is significantly associated with the RNA expression of many other genes, with 17,734 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR1F-associated genes across cancer lineages are CCNB1IP1, GARS1, and EIF3B. Each is linked with POLR1F in more than 5 cancer types. Because this analysis shows association rather than direction, both POLR1F-to-partner and partner-to-POLR1F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR1F versus CCNB1IP1 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR1F→partner) and Y-score (partner→POLR1F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CCNB1IP1 →	+0.624	+0.296	<.001	<.001	3	6
LSCC	GARS1 →	+0.628	+0.348	<.001	<.001	3	6
LSCC	EIF3B →	+0.613	+0.357	<.001	<.001	3	6
LSCC	LSM5 →	+0.644	+0.249	<.001	<.001	3	6
HNSC	COA1 →	+0.452	+0.284	<.001	<.001	3	6
LUAD	FIGNL1 →	+0.665	+0.332	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,734 associations by consensus.

POLR1F vs CCNB1IP1 — LSCC

Explore this scatter interactively →