POLDIP2

Across TCGA cell cohorts, POLDIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,619 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible POLDIP2-associated GO terms across cancer lineages are Ubiquinone metabolic process, DNA replication initiation, and rRNA 5'-end processing. Each is linked with POLDIP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both POLDIP2-to-partner and partner-to-POLDIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ubiquinone metabolic process grouped by POLDIP2-low versus POLDIP2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLDIP2→partner) and Y-score (partner→POLDIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Ubiquinone metabolic process →	+0.092	+0.577	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.179	+0.877	<.001	<.001	3	11
PANCREAS	rRNA 5'-end processing →	+0.114	+0.770	<.001	<.001	3	10
PANCREAS	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.114	+0.770	<.001	<.001	3	10
BLOOD_Lymphoma	Ribosome assembly →	+0.076	+0.647	<.001	.001	3	10
PANCREAS	Double-strand break repair via break-induced replication →	+0.193	+0.621	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,619 associations by consensus.

Ubiquinone metabolic process by POLDIP2 expression — PANCREAS

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