POLD4

Across TCGA patient cohorts, POLD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,556 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POLD4-associated proteins across cancer lineages are CORO1B, SERPINB1, and ITGA3. Each is linked with POLD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both POLD4-to-partner and partner-to-POLD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLD4 versus CORO1B in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLD4→partner) and Y-score (partner→POLD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CORO1B →	+0.347	+0.452	<.001	.001	3	5
GBM	SERPINB1 →	+0.594	+0.430	<.001	<.001	3	4
GBM	ITGA3 →	+0.592	+0.342	<.001	<.001	3	4
LSCC	LMAN1 →	-0.380	-0.385	<.001	<.001	3	4
BRCA	MDN1 →	-0.440	-0.721	<.001	<.001	3	4
GBM	CAPN1 →	+0.233	+0.369	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,556 associations by consensus.

POLD4 vs CORO1B — HNSC

Explore this scatter interactively →