PODN

Across TCGA patient cohorts, PODN mutation is significantly associated with the RNA expression of many other genes, with 5,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PODN-associated genes across cancer lineages are RNA5SP233, RNU2-47P, and RNU7-196P. Each is linked with PODN in more than 2 cancer types. Because this analysis shows association rather than direction, both PODN-to-partner and partner-to-PODN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP233 grouped by PODN-low versus PODN-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PODN→partner) and Y-score (partner→PODN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP233 →	+0.535	+4.252	.006	.003	3	3
BLCA	RNU2-47P →	+0.219	+5.203	<.001	<.001	3	3
COAD	RNU7-196P →	+0.579	+4.518	<.001	<.001	3	3
READ	RNU6-198P →	+0.493	+5.421	<.001	.005	3	2
READ	CDK8P1 →	+0.112	+5.039	.001	.008	3	2
READ	EEF1E1-BLOC1S5 →	+0.204	+5.219	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,170 associations by consensus.

RNA5SP233 by PODN expression — LUAD

Explore this box plot interactively →