POC1B

Across TCGA cell cohorts, POC1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,301 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible POC1B-associated GO terms across cancer lineages are Regulation of centriole elongation, Positive regulation of centriole elongation, and Retina homeostasis. Each is linked with POC1B in more than 12 cancer types. Because this analysis shows association rather than direction, both POC1B-to-partner and partner-to-POC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole elongation grouped by POC1B-low versus POC1B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1B→partner) and Y-score (partner→POC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of centriole elongation →	+0.124	+1.000	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of centriole elongation →	+0.137	+0.992	<.001	.007	3	11
STOMACH	Retina homeostasis →	+0.075	+0.782	<.001	<.001	3	9
URINARY_TRACT	Positive regulation of lipid localization →	-0.070	-0.425	<.001	.009	3	8
LUNG_SCLC	Regulation of centriole replication →	+0.099	+0.570	<.001	.004	3	8
BREAST	Positive regulation of organelle assembly →	+0.060	+0.932	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,301 associations by consensus.

Regulation of centriole elongation by POC1B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →