POC1B

Across TCGA cell cohorts, POC1B mutation is significantly associated with the drug of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POC1B-associated genes across cancer lineages are 123829, CX-5461, and CD532. Each is linked with POC1B in more than 1 cancer types. Because this analysis shows association rather than direction, both POC1B-to-partner and partner-to-POC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123829 grouped by POC1B-low versus POC1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1B→partner) and Y-score (partner→POC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.605	+2.649	.038	.046	3	1
LARGE_INTESTINE	CX-5461 →	+0.670	+2.652	.023	.045	3	1
LARGE_INTESTINE	CD532 →	+0.526	+2.652	.008	.045	3	1
LARGE_INTESTINE	GSK2110183B →	+0.621	+2.649	.041	.046	2	1
LARGE_INTESTINE	OF-1 →	+0.346	+2.646	.016	.047	2	1
LARGE_INTESTINE	Dacarbazine →	+0.275	+2.777	.049	.038	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

123829 by POC1B expression — LARGE_INTESTINE

Explore this box plot interactively →