POC1B-GALNT4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, POC1B-GALNT4 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible POC1B-GALNT4-associated genes across cancer lineages are LCN1, OR5B3, and KRTAP11-1. Each is linked with POC1B-GALNT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both POC1B-GALNT4-to-partner and partner-to-POC1B-GALNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCN1 grouped by POC1B-GALNT4-low versus POC1B-GALNT4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1B-GALNT4→partner) and Y-score (partner→POC1B-GALNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaLCN1 →+0.057+4.922<.001.00931
SKINOR5B3 →+0.045+5.415<.001.00431
SKINKRTAP11-1 →+0.022+5.415<.001.00431
SKINAADACL3 →+0.006+4.977<.001.00731
SKINC3orf56 →+0.006+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

LCN1 by POC1B-GALNT4 expression — BLOOD_Leukemia

Box plot of LCN1 in POC1B-GALNT4-low vs POC1B-GALNT4-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration