POC1A

Across TCGA patient cohorts, POC1A mutation is significantly associated with the RNA expression of many other genes, with 772 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POC1A-associated genes across cancer lineages are BANF1P4, RNU6-178P, and MTHFD2P3. Each is linked with POC1A in more than 1 cancer types. Because this analysis shows association rather than direction, both POC1A-to-partner and partner-to-POC1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BANF1P4 grouped by POC1A-low versus POC1A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POC1A→partner) and Y-score (partner→POC1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	BANF1P4 →	+0.218	+3.847	.005	.005	3	2
UCEC	RNU6-178P →	+0.810	+2.874	<.001	.003	3	2
UCEC	MTHFD2P3 →	+0.180	+2.889	.001	.004	3	2
UCEC	USP9YP2 →	+0.026	+5.744	<.001	<.001	3	2
UCEC	RNA5SP418 →	+0.719	+2.377	<.001	.008	3	2
SKCM	MIR3667 →	+0.558	+3.825	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 772 associations by consensus.

BANF1P4 by POC1A expression — BLCA

Explore this box plot interactively →