PNPP1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PNPP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,324 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PNPP1-associated proteins across cancer lineages are RPS3, ARFGEF3_S2081, and VAPB_S146. Each is linked with PNPP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PNPP1-to-partner and partner-to-PNPP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PNPP1→partner) and Y-score (partner→PNPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRPS3 →-0.179-0.302<.001<.00132
GBMARFGEF3_S2081 →+0.734+0.354<.001<.00132
CCRCCVAPB_S146 →+0.618+0.061.005.00232
GBMBRK1 →+0.158+0.278.004.00732
GBMS100A4 →-0.636-0.283<.001<.00132
GBMSERINC1 →+0.288+0.225<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,324 associations by consensus.

Exploration