PNPLA5

Across TCGA patient cohorts, PNPLA5 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,226 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PNPLA5-associated proteins across cancer lineages are RALBP1, REPS1, and AHCTF1_S1232. Each is linked with PNPLA5 in more than 3 cancer types. Because this analysis shows association rather than direction, both PNPLA5-to-partner and partner-to-PNPLA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNPLA5 versus RALBP1 in GBM, with a Pearson correlation of 0.52.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PNPLA5→partner) and Y-score (partner→PNPLA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RALBP1 →	+0.234	+0.856	<.001	<.001	3	4
HNSC	REPS1 →	+0.260	+0.824	<.001	<.001	3	4
LSCC	AHCTF1_S1232 →	+0.453	+0.462	.001	<.001	2	4
PDAC	MAP7_S315 →	+0.571	+0.591	.001	.001	3	3
HNSC	SRSF4_S78 →	-1.151	-0.837	<.001	<.001	3	3
UCEC	TSC22D4_S279 →	+0.534	+0.475	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,226 associations by consensus.

PNPLA5 vs RALBP1 — GBM

Explore this scatter interactively →