PNPLA1

Across TCGA patient cohorts, PNPLA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,490 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PNPLA1-associated proteins across cancer lineages are S100A9_T113, FBXO38, and TSC22D3. Each is linked with PNPLA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PNPLA1-to-partner and partner-to-PNPLA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNPLA1 versus S100A9_T113 in PDAC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PNPLA1→partner) and Y-score (partner→PNPLA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	S100A9_T113 →	+1.146	+0.331	.001	.003	3	4
BRCA	FBXO38 →	-0.252	-0.151	.001	.001	3	4
LSCC	TSC22D3 →	-0.399	-0.519	<.001	<.001	3	3
HNSC	MAPK13 →	+0.355	+0.717	<.001	<.001	3	3
LSCC	VPS13C →	-0.219	-0.486	.002	.002	3	3
LSCC	ATP11B →	+0.339	+0.390	.005	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,490 associations by consensus.

PNPLA1 vs S100A9_T113 — PDAC

Explore this scatter interactively →