PNMT

Across TCGA cell cohorts, PNMT RNA expression is significantly associated with the RNA expression of many other genes, with 5,487 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PNMT-associated genes across cancer lineages are WNT11, SMIM1, and APOE. Each is linked with PNMT in more than 6 cancer types. Because this analysis shows association rather than direction, both PNMT-to-partner and partner-to-PNMT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PNMT versus WNT11 in STOMACH, with a Pearson correlation of 0.52.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMT→partner) and Y-score (partner→PNMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	WNT11 →	+3.013	+2.036	<.001	.002	2	7
BLOOD_Leukemia	SMIM1 →	+1.864	+1.448	<.001	<.001	3	5
SOFT_TISSUE	APOE →	+3.277	+0.205	<.001	<.001	2	5
BREAST	TCAP →	+1.584	+1.988	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	TRPC1 →	+1.057	+1.005	<.001	.002	3	3
BLOOD_Leukemia	C5AR2 →	+0.947	+1.128	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,487 associations by consensus.

PNMT vs WNT11 — STOMACH

Explore this scatter interactively →