Across TCGA patient cohorts, PNMA6E protein abundance is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PNMA6E-associated genes across cancer lineages are PABPN1, SGK3, and HAPLN1. Each is linked with PNMA6E in more than 1 cancer types. Because this analysis shows association rather than direction, both PNMA6E-to-partner and partner-to-PNMA6E results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNMA6E→partner) and Y-score (partner→PNMA6E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PABPN1 →	+0.585	+1.622	.007	.009	3	1
UCEC	SGK3 →	-0.746	-1.813	.002	.002	3	1
UCEC	HAPLN1 →	+1.891	+2.201	.002	.008	3	1
UCEC	TRIM7 →	+0.463	+2.376	.007	.003	3	1
UCEC	ABI3BP →	-1.966	-1.719	<.001	.009	3	1
UCEC	GDNF →	-0.521	-1.840	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration

PNMA6E survival (RNA) · tumor vs normal (RNA) · all PNMA6E data types