Across TCGA cell cohorts, PNLIPRP3 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible PNLIPRP3-associated genes across cancer lineages are GUCA2A, OR1A2, and OR3A1. Each is linked with PNLIPRP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PNLIPRP3-to-partner and partner-to-PNLIPRP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIPRP3→partner) and Y-score (partner→PNLIPRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	GUCA2A →	+0.028	+3.342	<.001	.008	3	1
LUNG_NSCLC_LUAD	OR1A2 →	+0.017	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR3A1 →	+0.977	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	OR1G1 →	+0.043	+5.189	<.001	<.001	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.019	+5.472	<.001	<.001	3	1
LUNG_NSCLC_LUAD	RTP2 →	+0.038	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

PNLIPRP3 survival (RNA) · tumor vs normal (RNA) · all PNLIPRP3 data types