PNLIPRP2

Across TCGA patient cohorts, PNLIPRP2 mutation is significantly associated with the RNA expression of many other genes, with 3,271 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PNLIPRP2-associated genes across cancer lineages are E2F1, CDC45, and SNHG30. Each is linked with PNLIPRP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PNLIPRP2-to-partner and partner-to-PNLIPRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, E2F1 grouped by PNLIPRP2-low versus PNLIPRP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIPRP2→partner) and Y-score (partner→PNLIPRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	E2F1 →	+0.763	+1.936	.001	.003	3	3
UCEC	CDC45 →	+0.818	+2.860	<.001	<.001	3	3
UCEC	SNHG30 →	+0.591	+2.008	<.001	.005	3	2
UCEC	PIGW →	+0.551	+2.439	.001	.001	3	2
SKCM	RN7SL299P →	+0.118	+4.732	<.001	<.001	3	2
HNSC	TAF9BP2 →	+0.072	+4.025	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,271 associations by consensus.

E2F1 by PNLIPRP2 expression — UCEC

Explore this box plot interactively →