PNLIPRP2

Across TCGA pan-cancer cohorts, PNLIPRP2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated PNLIPRP2 data layer compared with 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher PNLIPRP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PNLIPRP2 expression acts as an unfavorable survival marker, although some lineages such as UCS and READ show a favorable association.

UCEC, LIHC, and ACC are the cancer types where PNLIPRP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	All	0.877	0.944	<.001	54	view →
LIHC	OS	Tertile	II,III,IV	0.567	0.754	.005	33	view →
ACC	DFS	Tertile	II,III,IV	0.446	0.794	.002	30	view →
LUAD	OS	Tertile	III,IV	0.455	0.710	.016	30	view →
UCS	DFS	Median	II,III,IV	0.573	0.175	.001	28	view →
KIRC	DFS	Median	All	0.576	0.670	.010	23	view →
READ	DFS	Median	All	0.846	0.406	.004	18	view →
TGCT	DFS	Tertile	All	0.485	0.838	.002	18	view →
DLBC	DFS	Tertile	All	0.389	0.855	.007	15	view →
STAD	OS	Median	All	0.389	0.665	.011	14	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	13	view →
ESCA	OS	Quartile	All	0.493	1.000	.017	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

PNLIPRP2–UCEC (OS)

Open the UCEC breakdown →