PNLIPP1

Across TCGA patient cohorts, PNLIPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,258 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PNLIPP1-associated GO terms across cancer lineages are Protein insertion into membrane, Ribose phosphate biosynthetic process, and Mitochondrial gene expression. Each is linked with PNLIPP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both PNLIPP1-to-partner and partner-to-PNLIPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein insertion into membrane grouped by PNLIPP1-low versus PNLIPP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PNLIPP1→partner) and Y-score (partner→PNLIPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein insertion into membrane →	+0.083	+0.113	<.001	<.001	3	10
STAD	Ribose phosphate biosynthetic process →	+0.078	+0.097	<.001	<.001	3	10
STAD	Mitochondrial gene expression →	+0.092	+0.122	<.001	<.001	3	9
STAD	Regulation of DNA recombination →	+0.069	+0.109	<.001	<.001	3	9
STAD	Methylation →	+0.070	+0.112	<.001	<.001	3	9
STAD	Mitochondrial translation →	+0.095	+0.101	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,258 associations by consensus.

Protein insertion into membrane by PNLIPP1 expression — STAD

Explore this box plot interactively →