PMS2P3

Across TCGA patient cohorts, PMS2P3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PMS2P3-associated genes across cancer lineages are SDR42E1P4 and MIR4503. Each is linked with PMS2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both PMS2P3-to-partner and partner-to-PMS2P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SDR42E1P4 grouped by PMS2P3-low versus PMS2P3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMS2P3→partner) and Y-score (partner→PMS2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SDR42E1P4 →	+0.199	+8.066	<.001	.007	3	1
BRCA	MIR4503 →	+0.281	+7.731	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SDR42E1P4 by PMS2P3 expression — UCEC

Explore this box plot interactively →