PMS2P3

Across TCGA pan-cancer cohorts, PMS2P3 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of PMS2P3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where PMS2P3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types PMS2P3 is over-expressed in tumor.

COAD, HNSC, and LIHC are the cancer types where PMS2P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PMS2P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.024	<.001	10	view →
HNSC	Male	III,IV	+0.770	<.001	10	view →
LIHC	Female	II,III,IV	+0.996	<.001	9	view →
KIRC	Male	II,III,IV	+0.380	<.001	9	view →
READ	All	All	+0.890	<.001	7	view →
BLCA	All	III,IV	+0.737	.001	7	view →
LUAD	Male	All	+0.603	<.001	7	view →
STAD	All	II,III,IV	+0.700	<.001	6	view →
UCEC	All	II,III,IV	+0.685	<.001	6	view →
CHOL	All	All	+1.840	<.001	5	view →
ESCA	All	All	+0.762	.001	4	view →
LUSC	Male	All	+0.574	<.001	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

PMS2P3–COAD

Open the COAD breakdown →