PMM1

Across TCGA patient cohorts, PMM1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,086 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PMM1-associated genes across cancer lineages are A4GALT, ARFGAP3, and ST13. Each is linked with PMM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PMM1-to-partner and partner-to-PMM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMM1 versus A4GALT in PDAC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMM1→partner) and Y-score (partner→PMM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	A4GALT →	+0.940	+0.387	<.001	.001	3	5
BRCA	ARFGAP3 →	+0.670	+0.337	<.001	<.001	3	5
BRCA	ST13 →	+0.668	+0.401	<.001	<.001	3	4
GBM	CRYM →	+1.457	+0.381	<.001	<.001	3	4
GBM	FGF1 →	+1.000	+0.421	<.001	<.001	3	3
COAD	SYNC →	+0.752	+0.508	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,086 associations by consensus.

PMM1 vs A4GALT — PDAC

Explore this scatter interactively →