PMEPA1

Across TCGA patient cohorts, PMEPA1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,507 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PMEPA1-associated genes across cancer lineages are TWIST1, ABHD12, and E2F1. Each is linked with PMEPA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PMEPA1-to-partner and partner-to-PMEPA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PMEPA1 versus TWIST1 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PMEPA1→partner) and Y-score (partner→PMEPA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TWIST1 →	+1.628	+0.621	.007	.006	3	2
LSCC	ABHD12 →	-0.705	-0.464	.001	.005	3	1
LSCC	E2F1 →	-1.425	-0.587	.006	.008	3	1
LSCC	SRPX2 →	+1.111	+0.505	.004	.001	3	1
LSCC	IQCE →	-0.896	-0.501	.001	.001	3	1
LSCC	FUBP3 →	-0.465	-0.461	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,507 associations by consensus.

PMEPA1 vs TWIST1 — LSCC

Explore this scatter interactively →