PLXND1

Across TCGA patient cohorts, PLXND1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,593 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLXND1-associated proteins across cancer lineages are STAB1, TIMP2, and NNMT. Each is linked with PLXND1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLXND1-to-partner and partner-to-PLXND1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXND1 versus STAB1 in GBM, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXND1→partner) and Y-score (partner→PLXND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STAB1 →	+0.574	+0.720	<.001	<.001	3	8
BRCA	TIMP2 →	+0.789	+0.714	<.001	<.001	3	7
GBM	NNMT →	+1.292	+0.786	<.001	<.001	3	7
OV	PCOLCE →	+0.942	+1.071	<.001	<.001	3	7
OV	PRKG1 →	+0.759	+1.095	<.001	.001	3	7
BRCA	RSU1 →	+0.314	+0.625	.002	.005	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,593 associations by consensus.

PLXND1 vs STAB1 — GBM

Explore this scatter interactively →