Across TCGA cell cohorts, PLXNB2 mutation is significantly associated with the RNA expression of many other genes, with 515 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLXNB2-associated genes across cancer lineages are RBMY1J, IL25, and TFDP3. Each is linked with PLXNB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLXNB2-to-partner and partner-to-PLXNB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNB2→partner) and Y-score (partner→PLXNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RBMY1J →	+0.035	+4.930	<.001	.008	3	2
LUNG_NSCLC_LUSC	IL25 →	+0.026	+4.643	<.001	.008	3	2
LUNG_NSCLC_LUSC	TFDP3 →	+0.006	+4.643	<.001	.008	3	2
BLOOD_Leukemia	FAM149A →	+1.292	+2.672	<.001	.004	3	2
BLOOD_Leukemia	OR10T2 →	+0.399	+2.206	.001	.009	3	2
BLOOD_Leukemia	OR10R2 →	+0.905	+2.481	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 515 associations by consensus.

Exploration

PLXNB2 survival (RNA) · tumor vs normal (RNA) · all PLXNB2 data types