PLXNA1

Across TCGA patient cohorts, PLXNA1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,159 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLXNA1-associated genes across cancer lineages are DSE, MYOSLID, and LNCAROD. Each is linked with PLXNA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLXNA1-to-partner and partner-to-PLXNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLXNA1 versus DSE in COAD, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA1→partner) and Y-score (partner→PLXNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DSE →	+0.677	+0.440	<.001	<.001	3	7
HNSC	MYOSLID →	+0.699	+0.227	.003	<.001	3	6
CCRCC	LNCAROD →	+0.672	+0.519	<.001	<.001	3	6
LSCC	ULBP2 →	+1.051	+0.182	<.001	.002	3	6
LSCC	PLD3 →	+0.592	+0.222	.001	.001	3	5
COAD	GSDME →	+0.831	+0.369	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,159 associations by consensus.

PLXNA1 vs DSE — COAD

Explore this scatter interactively →