PLXNA1

Across TCGA cell cohorts, PLXNA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,906 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PLXNA1-associated GO terms across cancer lineages are Schwann cell differentiation, Viral process, and Regulation of protein localization to nucleus. Each is linked with PLXNA1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PLXNA1-to-partner and partner-to-PLXNA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell differentiation grouped by PLXNA1-low versus PLXNA1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLXNA1→partner) and Y-score (partner→PLXNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Schwann cell differentiation →	+0.174	+2.251	<.001	<.001	3	15
BONE	Viral process →	+0.129	+2.099	<.001	<.001	3	15
STOMACH	Regulation of protein localization to nucleus →	+0.079	+1.659	.008	.004	3	15
OESOPHAGUS	mRNA alternative polyadenylation →	+0.128	+1.668	.004	.005	3	14
BLOOD_Lymphoma	Gonadotrophin-releasing hormone neuronal migration to the hypothalamus →	+0.964	+2.167	<.001	<.001	3	14
BLOOD_Lymphoma	Hypothalamus cell migration →	+0.980	+2.113	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,906 associations by consensus.

Schwann cell differentiation by PLXNA1 expression — URINARY_TRACT

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