PLTP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLTP RNA expression is significantly associated with the protein abundance of many other proteins, with 17,198 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLTP-associated proteins across cancer lineages are C1QC, F13A1, and MRC1. Each is linked with PLTP in more than 7 cancer types. Because this analysis shows association rather than direction, both PLTP-to-partner and partner-to-PLTP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLTP versus C1QC in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLTP→partner) and Y-score (partner→PLTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVC1QC →+0.730+0.953<.001.00338
CCRCCF13A1 →+0.751+1.280<.001<.00138
GBMMRC1 →+0.588+0.612<.001<.00137
GBMVSIG4 →+0.849+0.938<.001<.00137
OVC1QA →+0.641+1.012<.001.00128
CCRCCC1QB →+0.537+0.831<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,198 associations by consensus.

PLTP vs C1QC — OV

Per-sample scatter of PLTP vs C1QC in OV (Pearson r = 0.37).

Explore this scatter interactively →

Exploration