PLTP

Across TCGA cell cohorts, PLTP RNA expression is significantly associated with the RNA expression of many other genes, with 8,953 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLTP-associated genes across cancer lineages are APOE, GBGT1, and ARHGEF25. Each is linked with PLTP in more than 9 cancer types. Because this analysis shows association rather than direction, both PLTP-to-partner and partner-to-PLTP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLTP versus APOE in STOMACH, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLTP→partner) and Y-score (partner→PLTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	APOE →	+4.787	+3.121	<.001	.001	3	10
BLOOD_Leukemia	GBGT1 →	+1.630	+1.702	<.001	<.001	3	8
OESOPHAGUS	ARHGEF25 →	+2.327	+3.597	<.001	.001	2	9
LUNG_SCLC	PPP1R14A →	+2.556	+1.631	<.001	<.001	3	7
KIDNEY	CORO6 →	+2.568	+3.144	<.001	<.001	3	7
LUNG_SCLC	ICAM5 →	+1.961	+1.874	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,953 associations by consensus.

PLTP vs APOE — STOMACH

Explore this scatter interactively →