PLTP

Across TCGA cell cohorts, PLTP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,149 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLTP-associated GO terms across cancer lineages are High-density lipoprotein particle remodeling, AMPA glutamate receptor clustering, and Glutamate receptor clustering. Each is linked with PLTP in more than 14 cancer types. Because this analysis shows association rather than direction, both PLTP-to-partner and partner-to-PLTP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, High-density lipoprotein particle remodeling grouped by PLTP-low versus PLTP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLTP→partner) and Y-score (partner→PLTP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	High-density lipoprotein particle remodeling →	+0.289	+2.162	.002	.001	3	15
KIDNEY	AMPA glutamate receptor clustering →	+1.557	+2.991	<.001	.001	3	14
KIDNEY	Glutamate receptor clustering →	+1.557	+2.991	<.001	.001	3	14
BLOOD_Leukemia	Protein-lipid complex remodeling →	+0.183	+2.135	<.001	<.001	3	13
BLOOD_Leukemia	Plasma lipoprotein particle remodeling →	+0.183	+2.135	<.001	<.001	3	13
OESOPHAGUS	Chylomicron remnant clearance →	+1.464	+4.112	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,149 associations by consensus.

High-density lipoprotein particle remodeling by PLTP expression — SOFT_TISSUE

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