PLSCR2

Across TCGA cell cohorts, PLSCR2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PLSCR2-associated genes across cancer lineages are OR1M1 and SERPINB11. Each is linked with PLSCR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLSCR2-to-partner and partner-to-PLSCR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1M1 grouped by PLSCR2-low versus PLSCR2-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLSCR2→partner) and Y-score (partner→PLSCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR1M1 →	+0.010	+4.058	<.001	.007	3	1
LUNG_SCLC	SERPINB11 →	+0.032	+3.523	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR1M1 by PLSCR2 expression — LUNG_SCLC

Explore this box plot interactively →