PLS3-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLS3-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,824 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PLS3-AS1-associated proteins across cancer lineages are PLS3, CAMSAP2, and CRACR2A. Each is linked with PLS3-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLS3-AS1-to-partner and partner-to-PLS3-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLS3-AS1 versus PLS3 in GBM, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLS3-AS1→partner) and Y-score (partner→PLS3-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMPLS3 →+0.684+0.642<.001<.00137
LSCCCAMSAP2 →+0.359+0.478<.001<.00135
BRCACRACR2A →-0.423-0.421<.001<.00134
HNSCCXorf56 →+0.244+0.610.005<.00134
HNSCDHX9 →+0.253+0.830<.001<.00134
BRCADNAJC1 →-0.505-0.365<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,824 associations by consensus.

PLS3-AS1 vs PLS3 — GBM

Per-sample scatter of PLS3-AS1 vs PLS3 in GBM (Pearson r = 0.60).

Explore this scatter interactively →

Exploration