PLS1

Across TCGA patient cohorts, PLS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,959 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLS1-associated proteins across cancer lineages are RBM47, CD14, and PKP4. Each is linked with PLS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PLS1-to-partner and partner-to-PLS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLS1 versus RBM47 in UCEC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLS1→partner) and Y-score (partner→PLS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RBM47 →	+0.376	+0.648	<.001	<.001	3	7
CCRCC	CD14 →	-0.430	-0.796	<.001	<.001	3	7
BRCA	PKP4 →	+0.304	+0.688	.006	.002	3	6
LUAD	PLEKHA7_S903 →	+0.654	+0.806	<.001	<.001	3	6
CCRCC	PLEKHA7 →	+0.402	+1.257	<.001	<.001	3	6
BRCA	THEMIS2 →	-0.343	-0.810	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,959 associations by consensus.

PLS1 vs RBM47 — UCEC

Explore this scatter interactively →