PLS1-AS1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PLS1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,334 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PLS1-AS1-associated proteins across cancer lineages are PLS1, RBM47, and WRNIP1. Each is linked with PLS1-AS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PLS1-AS1-to-partner and partner-to-PLS1-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLS1-AS1 versus PLS1 in HNSC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLS1-AS1→partner) and Y-score (partner→PLS1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCPLS1 →+1.107+1.161<.001<.00136
HNSCRBM47 →+0.299+0.706.009<.00133
LSCCWRNIP1 →+0.321+0.644<.001<.00133
OVALKBH5 →+0.601+0.147<.001.00833
HNSCC1orf226_S198 →+0.858+0.743<.001<.00133
LUADCD14 →-0.267-0.547<.001.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,334 associations by consensus.

PLS1-AS1 vs PLS1 — HNSC

Per-sample scatter of PLS1-AS1 vs PLS1 in HNSC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration