PLPPR1

Across TCGA patient cohorts, PLPPR1 protein abundance is significantly associated with the RNA expression of many other genes, with 495 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLPPR1-associated genes across cancer lineages are TOM1, SOS2, and PPP1R16B. Each is linked with PLPPR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLPPR1-to-partner and partner-to-PLPPR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLPPR1 versus TOM1 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPPR1→partner) and Y-score (partner→PLPPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TOM1 →	-0.406	-0.827	.002	.001	3	1
GBM	SOS2 →	+0.357	+0.743	.005	.001	3	1
GBM	PPP1R16B →	+1.160	+0.662	.003	.002	3	1
GBM	PLLP →	+0.879	+0.787	.002	.003	3	1
GBM	MTMR9 →	+0.359	+0.760	.006	.001	3	1
GBM	TUBB4A →	+1.412	+0.772	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 495 associations by consensus.

PLPPR1 vs TOM1 — GBM

Explore this scatter interactively →