PLPP7

Across TCGA patient cohorts, PLPP7 mutation is significantly associated with the RNA expression of many other genes, with 1,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PLPP7-associated genes across cancer lineages are LINC02745, RNU6-267P, and RNA5SP411. Each is linked with PLPP7 in more than 2 cancer types. Because this analysis shows association rather than direction, both PLPP7-to-partner and partner-to-PLPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02745 grouped by PLPP7-low versus PLPP7-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP7→partner) and Y-score (partner→PLPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	LINC02745 →	+0.101	+5.000	<.001	.009	3	3
LUSC	RNU6-267P →	+0.661	+3.919	<.001	.006	3	3
UCEC	RNA5SP411 →	+1.078	+1.808	<.001	.007	3	2
HNSC	RN7SKP246 →	+0.150	+5.111	<.001	.004	3	2
PRAD	OR7E159P →	+0.173	+6.593	<.001	.001	3	2
LUAD	RNU6-747P →	+0.283	+7.930	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,196 associations by consensus.

LINC02745 by PLPP7 expression — PRAD

Explore this box plot interactively →