PLPP7

Across TCGA cell cohorts, PLPP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,062 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLPP7-associated GO terms across cancer lineages are Calcium-independent cell-matrix adhesion, Protein folding, and Regulation of mesenchymal stem cell proliferation. Each is linked with PLPP7 in more than 7 cancer types. Because this analysis shows association rather than direction, both PLPP7-to-partner and partner-to-PLPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium-independent cell-matrix adhesion grouped by PLPP7-low versus PLPP7-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP7→partner) and Y-score (partner→PLPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Calcium-independent cell-matrix adhesion →	+0.129	+1.462	<.001	<.001	3	8
BONE	Protein folding →	+0.078	+1.831	<.001	<.001	3	7
BONE	Regulation of mesenchymal stem cell proliferation →	+0.264	+1.697	<.001	.001	3	6
BONE	Positive regulation of mesenchymal stem cell proliferation →	+0.264	+1.697	<.001	.001	3	6
CNS	Regulation of DNA-templated transcription initiation →	+0.053	+1.481	<.001	<.001	3	6
SKIN	Sensory perception of mechanical stimulus →	-0.066	-1.312	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

Calcium-independent cell-matrix adhesion by PLPP7 expression — SKIN

Explore this box plot interactively →