PLPP7

Across TCGA cell cohorts, PLPP7 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PLPP7-associated genes across cancer lineages are KRTAP10-7, HRG, and FATE1. Each is linked with PLPP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both PLPP7-to-partner and partner-to-PLPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-7 grouped by PLPP7-low versus PLPP7-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP7→partner) and Y-score (partner→PLPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	KRTAP10-7 →	+0.020	+4.285	<.001	.007	3	1
BLOOD_Leukemia	HRG →	+0.357	+3.855	<.001	.007	3	1
BLOOD_Leukemia	FATE1 →	+0.100	+3.551	<.001	.009	3	1
BLOOD_Leukemia	ZIC3 →	+0.015	+4.060	<.001	.003	3	1
BLOOD_Leukemia	TPD52L3 →	+0.013	+5.124	<.001	<.001	3	1
BLOOD_Leukemia	DELEC1 →	+0.551	+3.855	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

KRTAP10-7 by PLPP7 expression — STOMACH

Explore this box plot interactively →