PLPP3

Across TCGA cell cohorts, PLPP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,412 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PLPP3-associated GO terms across cancer lineages are Viral process, Viral life cycle, and Sphingoid metabolic process. Each is linked with PLPP3 in more than 10 cancer types. Because this analysis shows association rather than direction, both PLPP3-to-partner and partner-to-PLPP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral process grouped by PLPP3-low versus PLPP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PLPP3→partner) and Y-score (partner→PLPP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Viral process →	+0.114	+4.528	<.001	<.001	3	11
BONE	Viral life cycle →	+0.109	+4.290	<.001	<.001	3	11
URINARY_TRACT	Sphingoid metabolic process →	+0.106	+1.704	<.001	<.001	3	11
SOFT_TISSUE	Biological process involved in symbiotic interaction →	+0.083	+2.221	.001	.002	3	11
BONE	Negative regulation of neuron apoptotic process →	+0.096	+3.715	.001	<.001	3	10
SKIN	Cotranslational protein targeting to membrane →	+0.099	+1.347	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,412 associations by consensus.

Viral process by PLPP3 expression — BONE

Explore this box plot interactively →