PLOD3

Across TCGA patient cohorts, PLOD3 protein abundance is significantly associated with the RNA expression of many other genes, with 19,628 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PLOD3-associated genes across cancer lineages are FNDC3B, P3H1, and CALU. Each is linked with PLOD3 in more than 8 cancer types. Because this analysis shows association rather than direction, both PLOD3-to-partner and partner-to-PLOD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLOD3 versus FNDC3B in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PLOD3→partner) and Y-score (partner→PLOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FNDC3B →	+0.819	+0.637	<.001	<.001	3	9
OV	P3H1 →	+1.155	+0.350	<.001	<.001	3	8
CCRCC	CALU →	+0.731	+0.556	<.001	<.001	3	8
LSCC	LOXL2 →	+1.225	+0.447	<.001	<.001	3	8
HNSC	P4HA2 →	+0.869	+0.477	.002	<.001	3	8
GBM	TGFBI →	+1.159	+0.475	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,628 associations by consensus.

PLOD3 vs FNDC3B — BRCA

Explore this scatter interactively →